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CS-W001157 4
Total: USD 88.00

2,5-Dioxopyrrolidin-1-yl decanoate

  • CAS No. 22102-66-5

  • Cat. No. CS-0179395
  • Purity≥97%
  • MDL No.MFCD00673470

*For research and further manufacturing use only, not for direct human use.

2,5-Dioxopyrrolidin-1-yl decanoate|CS-0179395

Structure of 22102-66-5

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General Information

  • CAS No. 22102-66-5
  • Cat. No. CS-0179395
  • Purity ≥97%
  • MDL No. MFCD00673470
  • Storage -20°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₄H₂₃NO₄
  • Molecular Weight 269.34
  • Synonym(s) Decanoic acid, 2,5-dioxo-1-pyrrolidinyl ester
  • SMILES CCCCCCCCCC(ON1C(CCC1=O)=O)=O

Description

This decanoate ester features a 2,5-dioxopyrrolidin-1-yl (DOP) leaving group engineered for high reactivity in amide bond formation. The long aliphatic chain imparts enhanced solubility in organic media while maintaining stability under standard bench conditions. Ideal for coupling reactions requiring efficient activation and clean deprotection.

Application

2,5-Dioxopyrrolidin-1-yl decanoate serves as a stable, bench-friendly acylating agent that facilitates efficient esterification and amide coupling reactions. Its activated ester functionality enables reliable conjugation with alcohols and amines under mild conditions, offering excellent functional group tolerance and ease of purification. This reagent is particularly valuable in peptide synthesis and the construction of complex molecular scaffolds where controlled reactivity and high yield are essential.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P280-P302+P352

Quality Control

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Computational Chemistry Data

  • TPSA   63.68
  • LogP   2.7343
  • H_Acceptors   4
  • H_Donors   0
  • Rotatable_Bonds   9

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