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CS-W001157 4
Total: USD 88.00

2-Bromo-1,1-difluorocyclopentane

  • CAS No. 2303705-25-9

  • Cat. No. CS-0377806
  • Purity≥97%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

2-Bromo-1,1-difluorocyclopentane|CS-0377806

Structure of 2303705-25-9

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General Information

  • CAS No. 2303705-25-9
  • Cat. No. CS-0377806
  • Purity ≥97%
  • MDL No. None
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₅H₇BrF₂
  • Molecular Weight 185.01
  • Synonym(s) None
  • SMILES FC1(F)C(Br)CCC1

Description

2-Bromo-1,1-difluorocyclopentane is a fluorinated cyclopentane derivative featuring bromine and two fluorine atoms at adjacent ring positions. This configuration imparts high polarity and enhanced metabolic stability, enabling its use in synthetic routes to bioactive molecules. The compound serves as a key building block for pharmaceutical intermediates and specialty materials where controlled reactivity and stereochemical integrity are essential.

Application

2-Bromo-1,1-difluorocyclopentane serves as a versatile fluorinated building block for medicinal chemistry and agrochemical synthesis. Its constrained cyclopentane core supports stereoselective transformations, while the geminal difluoro and bromo substituents enable palladium-catalyzed cross-coupling and subsequent functionalization. The molecule exhibits good bench stability and facilitates access to fluorinated heterocycles and bioactive scaffolds via standard synthetic protocols.

Safety Information

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GHS Pictogram :
GHS No : GHS02,GHS07
Signal Word : Danger
UN#: 1993
Class : 3
Packing Group : Ⅱ
Hazard Statements : H226-H315-H319-H335
Precautionary Statements : P210-P240-P241-P242-P243-P261-P264-P271-P280-P302+P352-P304+P340-P362-P370+P378-P405-P501

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Computational Chemistry Data

  • TPSA   0
  • LogP   2.5691
  • H_Acceptors   0
  • H_Donors   0
  • Rotatable_Bonds   0

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