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CS-W001157 4
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4-Methyl-3,4-dihydro-2H-benzo[b][1,4]oxazin-7-amine

  • CAS No. 220844-82-6

  • Cat. No. CS-0102545
  • Purity≥95%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

4-Methyl-3,4-dihydro-2H-benzo[b][1,4]oxazin-7-amine|CS-0102545

Structure of 220844-82-6

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General Information

  • CAS No. 220844-82-6
  • Cat. No. CS-0102545
  • Purity ≥95%
  • MDL No. None
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₁₂N₂O
  • Molecular Weight 164.20
  • Synonym(s) 7-amino-4-methyl-2H-1,4-benzoxazine
  • SMILES NC1=CC=C2N(C)CCOC2=C1

Synthesis

  • Route1

    References

    • Higuchi, Robert I.; Arienti, Kristen L.; Lopez, Francisco J.; Mani, Neelakhanda S.; Mais, Dale E.; Caferro, Thomas R.; Long, Yun Oliver; Jones, Todd K.; Edwards, James P.; Zhi, Lin; Schrader, William T.; Negro-Vilar, Andres; Marschke, Keith B. Journal of Medicinal Chemistry, 2007 , vol. 50, # 10 p. 2486 - 2496
  • Route2

    References

    • ASTRAZENECA AB; ASTRAZENECA UK LIMITED Patent: WO2006/40526 A1, 2006 ; Location in patent: Page/Page column 179 ; WO 2006/040526 A1
  • Route3

    References

    • Chapleo, Christopher B.; Butler, Richard C. M.; England, David C.; Myers, Peter L.; Roach, Alan G.; et al. Journal of Medicinal Chemistry, 1989 , vol. 32, # 7 p. 1627 - 1630

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302
Precautionary Statements : P264-P270-P330-P501

Quality Control

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Computational Chemistry Data

  • TPSA   38.49
  • LogP   1.0974
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   0

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