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CS-W001157 4
Total: USD 88.00

Lenalidomide-I

  • CAS No. 2207541-30-6

  • Cat. No. CS-0133087
  • Purity≥95%
  • MDL No.MFCD32862119

*For research and further manufacturing use only, not for direct human use.

Lenalidomide-I|CS-0133087

Structure of 2207541-30-6

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General Information

  • CAS No. 2207541-30-6
  • Cat. No. CS-0133087
  • Purity ≥95%
  • MDL No. MFCD32862119
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₃H₁₁IN₂O₃
  • Molecular Weight 370.14
  • Synonym(s) None
  • SMILES O=C(C(N(CC1=C2C=CC=C1I)C2=O)CC3)NC3=O

Description

Lenalidomide-I features a potent immunomodulatory scaffold with enhanced solubility and metabolic stability. This derivative integrates a critical imide moiety that enables selective binding to cereblon, modulating ubiquitin ligase activity. Designed for targeted protein degradation workflows, it offers improved handling under standard bench conditions.

Application

Lenalidomide-I serves as a key intermediate in the synthesis of immunomodulatory drug candidates, leveraging its imide and amine functionalities for robust coupling reactions. It exhibits excellent bench stability and facilitates efficient incorporation into diverse heterocyclic scaffolds via standard amide bond formation or reductive amination protocols. The molecule’s defined stereochemistry and functional group tolerance enable reliable downstream transformations in medicinal chemistry workflows.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   66.48
  • LogP   0.3761
  • H_Acceptors   5
  • H_Donors   1
  • Rotatable_Bonds   1

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