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CS-W001157 4
Total: USD 88.00

2-(2-(Benzyloxy)phenyl)acetic acid

  • CAS No. 22047-88-7

  • Cat. No. CS-0156164
  • Purity≥98%
  • MDL No.MFCD00016822

*For research and further manufacturing use only, not for direct human use.

2-(2-(Benzyloxy)phenyl)acetic acid|CS-0156164

Structure of 22047-88-7

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General Information

  • CAS No. 22047-88-7
  • Cat. No. CS-0156164
  • Purity ≥98%
  • MDL No. MFCD00016822
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₅H₁₄O₃
  • Molecular Weight 242.27
  • Synonym(s) 2-Benzyloxyphenylacetic acid
  • SMILES C1=CC=C(C=C1)COC2=CC=CC=C2CC(=O)O

Description

This benzyloxy-substituted phenylacetic acid features a strategically positioned benzyl ether that enhances solubility and stability in organic synthesis. The ortho-alkoxy group directs electrophilic substitution and enables efficient coupling reactions, making it a valuable scaffold for pharmaceutical intermediates and functional materials.

Application

2-(2-(Benzyloxy)phenyl)acetic acid serves as a versatile building block for medicinal chemistry and heterocyclic synthesis, enabling the construction of bioactive scaffolds through standard functional group transformations. Its benzyloxy-substituted aryl moiety provides enhanced solubility and metabolic stability, while the carboxylic acid functionality facilitates coupling reactions and derivatization under mild conditions. The compound exhibits good bench stability and is amenable to purification via recrystallization or chromatography, making it suitable for scalable synthesis workflows.

Safety Information

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GHS Pictogram :
GHS No : GHS05,GHS09
Signal Word : Danger
UN#: 3077
Class : 9
Packing Group : Ⅲ
Hazard Statements : H302-H315-H318-H335-H400
Precautionary Statements : P273-P280-P302+P352-P330

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Computational Chemistry Data

  • TPSA   46.53
  • LogP   2.8927
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   5

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