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Structure of 22047-86-5
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4,6-Dimethylnicotinic acid is a sterically hindered, bench-stable pyridine carboxylic acid featuring two methyl groups at the 4- and 6-positions. This substitution pattern enhances metabolic stability and modulates electronic properties, making it valuable for medicinal chemistry applications. The molecule integrates readily into bioactive scaffolds and serves as a key building block in the synthesis of pharmaceutical intermediates and functionalized heterocycles.
4,6-Dimethylnicotinic acid serves as a versatile building block in medicinal chemistry and agrochemical synthesis, enabling the construction of substituted pyridine scaffolds through standard functional group transformations. Its ortho-methyl groups enhance metabolic stability and influence electronic properties, while the carboxylic acid functionality facilitates direct derivatization or coupling reactions. The compound exhibits good bench stability and is amenable to purification via recrystallization, supporting its use in scalable synthetic workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: