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Structure of 220022-94-6
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2-(Dimethylamino)-2-methylpropanoic acid features a sterically hindered tertiary carbon bearing both a carboxylic acid and a dimethylamino group, enabling robust nucleophilic reactivity. This structural motif delivers enhanced solubility in polar solvents and stability under standard bench conditions, making it ideal for use in peptide coupling and synthetic transformations requiring controlled basicity.
2-(Dimethylamino)-2-methylpropanoic acid serves as a versatile building block in peptide synthesis and medicinal chemistry, offering a sterically hindered α-amino acid surrogate with enhanced solubility and stability. Its tertiary amine functionality enables facile salt formation and facilitates purification, while the carboxylic acid group supports standard coupling reactions. This compound functions effectively in solid-phase synthesis and is compatible with common protecting group strategies, making it a practical choice for constructing complex molecular architectures.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362-P405-P501
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Lot numbers can be found on the outside label of a product: