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CS-W001157 4
Total: USD 88.00

(R)-2-(Dimethylamino)propanoic acid

  • CAS No. 157431-09-9

  • Cat. No. CS-0158218
  • Molecule weight117.15
  • Purity≥97%
  • MDL No.MFCD19238066

*For research and further manufacturing use only, not for direct human use.

(R)-2-(Dimethylamino)propanoic acid|CS-0158218

Structure of 157431-09-9

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General Information

  • CAS No. 157431-09-9
  • Cat. No. CS-0158218
  • Purity ≥97%
  • MDL No. MFCD19238066
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₅H₁₁NO₂
  • Molecular Weight 117.15
  • Synonym(s) (-)-N,N-diisopropyl-3-(2-benzyloxy-5-carbomethoxyphenyl)-3-phenylpropylamine
  • SMILES C[C@H](C(=O)O)N(C)C

Description

(R)-2-(Dimethylamino)propanoic acid is a chiral building block featuring a stereodefined α-amino acid scaffold with a dimethylamino group at the β-position. This configuration imparts enhanced solubility and stability under physiological conditions, enabling efficient incorporation into peptide sequences and bioactive molecule synthesis.

Application

(R)-2-(Dimethylamino)propanoic acid serves as a valuable chiral building block in medicinal chemistry, enabling the synthesis of bioactive molecules through established peptide coupling and functional group transformation protocols. Its bench-stable nature and compatibility with standard protecting group strategies facilitate efficient access to diverse heterocyclic scaffolds and API intermediates.

Synthesis

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    • In-stock
      (R)-2-(Dimethylamino)propanoic acid|CS-0158218
      157431-09-9

    References

    • Schowen,K.B. et al. Journal of Medicinal Chemistry, 1975 , vol. 18, p. 292 - 300
  • Route2
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    • In-stock
      (R)-2-(Dimethylamino)propanoic acid|CS-0158218
      157431-09-9

    References

    • Bowman; Stroud Journal of the Chemical Society, 1950 , p. 1342,1345
  • Route3

    References

    • Beckett,A.H. et al. Journal of Pharmacy and Pharmacology, 1963 , vol. 15, p. 349 - 361

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   40.54
  • LogP   0.0211
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   2

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