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CS-W001157 4
Total: USD 88.00

(4-methoxy-1-naphthyl)boronic acid

  • CAS No. 219834-95-4

  • Cat. No. CS-0061977
  • Purity≥97%
  • MDL No.MFCD03452757

*For research and further manufacturing use only, not for direct human use.

(4-methoxy-1-naphthyl)boronic acid|CS-0061977

Structure of 219834-95-4

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General Information

  • CAS No. 219834-95-4
  • Cat. No. CS-0061977
  • Purity ≥97%
  • MDL No. MFCD03452757
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₁H₁₁BO₃
  • Molecular Weight 202.02
  • Synonym(s) 4-Methoxy-1-naphthaleneboronic acid
  • SMILES COC1=CC=C(C2=CC=CC=C21)B(O)O

Description

This boronic acid features a methoxy-substituted naphthyl group, delivering enhanced solubility and stability in polar solvents. The electron-donating methoxy moiety improves reaction kinetics in Suzuki-Miyaura couplings. Bench-stable under standard conditions, it integrates seamlessly into synthetic workflows requiring reliable coupling efficiency and minimal handling complexity.

Application

(4-methoxy-1-naphthyl)boronic acid serves as a reliable building block for Suzuki-Miyaura cross-coupling reactions, enabling efficient C–C bond formation under mild conditions. Its naphthyl scaffold provides enhanced π-conjugation and stability, while the methoxy group offers moderate electron-donating character and improved solubility. The boronic acid functions reliably in diverse reaction environments, facilitating access to complex aromatic architectures with high reproducibility and ease of purification.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P280-P302+P352

Quality Control

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Computational Chemistry Data

  • TPSA   49.69
  • LogP   0.5282
  • H_Acceptors   3
  • H_Donors   2
  • Rotatable_Bonds   2

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