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CS-W001157 4
Total: USD 88.00

(4-Methylnaphthalen-1-yl)boronic acid

  • CAS No. 103986-53-4

  • Cat. No. CS-W016926
  • Purity≥97%
  • MDL No.MFCD01632204

*For research and further manufacturing use only, not for direct human use.

(4-Methylnaphthalen-1-yl)boronic acid|CS-W016926

Structure of 103986-53-4

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General Information

  • CAS No. 103986-53-4
  • Cat. No. CS-W016926
  • Purity ≥97%
  • MDL No. MFCD01632204
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₁H₁₁BO₂
  • Molecular Weight 186.01
  • Synonym(s) 4-Methyl-1-naphthylboronic Acid (contains varying amounts of Anhydride)
  • SMILES OB(C1=C2C=CC=CC2=C(C)C=C1)O

Description

Boc-NH-ethyl-SS-propionic acid is a cleavable crboxylic acid linker. The terminal carboxylic acid group can be reacted with a primary amine in the presence of activators such as EDC and HATU to form stable amide bonds. The boc protecting group can be removed under acidic conditions to release the free amine for further reaction.

Synthesis

  • Route1
    • null|null
      5419-55-6
    • In-stock
      1-Bromo-4-methylnaphthalene|CS-0059152
      6627-78-7
    • ~95%
    • In-stock
      (4-Methylnaphthalen-1-yl)boronic acid|CS-W016926
      103986-53-4

    References

    • Tetrahedron, , vol. 68, # 46 p. 9371 - 9375,5
  • Route2
    • null|null
      150-46-9
    • In-stock
      1-Bromo-4-methylnaphthalene|CS-0059152
      6627-78-7
    • ~%
    • In-stock
      (4-Methylnaphthalen-1-yl)boronic acid|CS-W016926
      103986-53-4

    References

    • US2001/49379 A1, ;
  • Route3

    References

    • Chemistry - A European Journal, , vol. 12, # 33 p. 8609 - 8613

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   40.46
  • LogP   0.82802
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   1

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