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Structure of 219715-44-3
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2-Methoxypyridine-3-sulfonyl chloride is a reactive sulfonyl chloride derivative featuring a methoxy-substituted pyridine scaffold. This bench-stable reagent enables direct incorporation of electron-deficient sulfonyl groups into synthetic intermediates, facilitating efficient derivatization in pharmaceutical and agrochemical process development.
2-Methoxypyridine-3-sulfonyl chloride serves as a versatile sulfonylating agent for the efficient introduction of a pyridylsulfonyl group into diverse substrates. Its reactivity enables direct functionalization of nucleophiles such as amines and alcohols under mild conditions, offering high chemoselectivity and excellent yield in standard synthetic workflows. The methoxy substituent enhances solubility and modulates electronic properties, facilitating downstream transformations in medicinal chemistry and process development. This reagent exhibits good bench stability and is compatible with common protecting groups, making it ideal for modular heterocycle synthesis and API intermediate construction.
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GHS Pictogram :
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GHS No : GHS05
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Signal Word : Danger
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UN#: 3261
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Class : 8
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Packing Group : Ⅲ
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Hazard Statements : H314
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Precautionary Statements : P260-P280-P301+P330+P331-P304+P340
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Lot numbers can be found on the outside label of a product: