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CS-W001157 4
Total: USD 88.00

3,5-Dibromopyrazin-2-ol

  • CAS No. 21943-15-7

  • Cat. No. CS-W003394
  • Purity≥98%
  • MDL No.MFCD07371406
  • HazMat Fee +

    HazMat Fee

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

    The shipment is processed through FedEx Ground under the Limited Quantity option.

    Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

    If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

    There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

3,5-Dibromopyrazin-2-ol|CS-W003394

Structure of 21943-15-7

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Description

3,5-Dibromopyrazin-2-ol features two bromine atoms at the 3 and 5 positions of the pyrazinone ring, creating a highly functionalized heterocyclic scaffold. This electron-deficient platform enables direct coupling in cross-coupling reactions and serves as a key building block for advanced pharmaceutical intermediates and functional materials. The hydroxyl group enhances solubility and provides a handle for further derivatization under mild conditions.

Application

3,5-Dibromopyrazin-2-ol serves as a versatile building block for the synthesis of brominated heterocyclic scaffolds, enabling efficient late-stage functionalization in medicinal chemistry and materials science. Its stability under standard reaction conditions, combined with orthogonal reactivity of the pyrazinone core and bromide handles, facilitates palladium-catalyzed cross-coupling and nucleophilic substitution reactions. The compound functions effectively in the construction of complex nitrogen-containing frameworks relevant to pharmaceutical intermediates and advanced organic semiconductors.

General Information

  • CAS No. 21943-15-7
  • Cat. No. CS-W003394
  • Purity ≥98%
  • MDL No. MFCD07371406
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₄H₂Br₂N₂O
  • Molecular Weight 253.88
  • Synonym(s) 3,5-Dibromo-2-hydroxypyrazine
  • SMILES O=C1C(Br)=NC(Br)=CN1

Computational Chemistry Data

  • TPSA   45.75
  • LogP   1.2949
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   0

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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