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CS-W001157 4
Total: USD 88.00

m-Nifedipine

  • CAS No. 21881-77-6

  • Cat. No. CS-0111835
  • Purity≥95%
  • MDL No.MFCD00195480

*For research and further manufacturing use only, not for direct human use.

m-Nifedipine|CS-0111835

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General Information

  • CAS No. 21881-77-6
  • Cat. No. CS-0111835
  • Purity ≥95%
  • MDL No. MFCD00195480
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₇H₁₈N₂O₆
  • Molecular Weight 346.33
  • Synonym(s) None
  • SMILES O=C(C1=C(C)NC(C)=C(C(OC)=O)C1C2=CC=CC([N+]([O-])=O)=C2)OC

Description

m-Nifedipine features a meta-substituted pyridine core with a nitro group positioned ortho to the dihydropyridine ring, enhancing electron-withdrawing character. This configuration improves metabolic stability and facilitates selective calcium channel modulation in cardiovascular research applications.

Application

m-Nifedipine serves as a well-established dihydropyridine scaffold for calcium channel modulator research, enabling direct evaluation of substitution effects on vascular smooth muscle activity. Its bench-stable crystalline form facilitates reproducible synthesis and purification, while the ortho-dialkylated pyridine core supports standard functional group interconversions and metal-catalyzed coupling reactions in medicinal chemistry workflows.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302
Precautionary Statements : P264-P270-P330-P501

Quality Control

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Computational Chemistry Data

  • TPSA   107.77
  • LogP   2.1756
  • H_Acceptors   7
  • H_Donors   1
  • Rotatable_Bonds   4

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