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CS-W001157 4
Total: USD 88.00

Perchloropyridine

  • CAS No. 2176-62-7

  • Cat. No. CS-W010210
  • Purity≥98%
  • MDL No.MFCD00006230

*For research and further manufacturing use only, not for direct human use.

Perchloropyridine|CS-W010210

Structure of 2176-62-7

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General Information

  • CAS No. 2176-62-7
  • Cat. No. CS-W010210
  • Purity ≥98%
  • MDL No. MFCD00006230
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₅Cl₅N
  • Molecular Weight 251.31
  • Synonym(s) Pentachloropyridine
  • SMILES ClC1=NC(Cl)=C(Cl)C(Cl)=C1Cl

Application

Perchloropyridine serves as a versatile electrophilic building block in synthetic organic chemistry, enabling direct functionalization of pyridine rings under mild conditions. Its high reactivity facilitates efficient C–H substitution and heterocycle elaboration, particularly in transition-metal-catalyzed transformations. The molecule exhibits excellent bench stability and compatibility with common protecting groups, making it well-suited for iterative synthesis workflows and scalable API intermediate development.

Synthesis

  • Route1

    References

    • Joshi, Ashutosh V.; Baidossi, Mubeen; Qafisheh, Nida; Chachashvili, Elsa; Sasson, Yoel Tetrahedron Letters, 2004 , vol. 45, # 26 p. 5061 - 5063
  • Route2
    • 2,3,5,6-Tetrachloro-4-iodopyridine|CS-0876115
      30332-35-5
    • ~4%
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      2,3,5,6-Tetrachloropyridine|CS-0128415
      2402-79-1
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      Perchloropyridine|CS-W010210
      2176-62-7
    • null|null
      18725-60-5

    References

    • Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), , p. 1682 - 1687
  • Route3

    References

    • Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), , p. 1682 - 1687

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07,GHS09
Signal Word : Warning
UN#: 3077
Class : 9
Packing Group : Ⅲ
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   12.89
  • LogP   4.3486
  • H_Acceptors   1
  • H_Donors   0
  • Rotatable_Bonds   0

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