Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

3-Phenoxypyridine

  • CAS No. 2176-45-6

  • Cat. No. CS-0060564
  • Purity≥98%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

3-Phenoxypyridine|CS-0060564

Structure of 2176-45-6

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

General Information

  • CAS No. 2176-45-6
  • Cat. No. CS-0060564
  • Purity ≥98%
  • MDL No. None
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₁H₉NO
  • Molecular Weight 171.20
  • Synonym(s) 3-PHENOXYPYRIDINE AND MONOSULFATE
  • SMILES C1=CC=C(C=C1)OC2=CN=CC=C2

Description

3-Phenoxypyridine serves as a key heterocyclic scaffold in medicinal chemistry, combining a pyridine core with a phenoxyl substituent that enhances solubility and modulates electronic properties. This structure facilitates integration into bioactive molecules, particularly those targeting kinase pathways and CNS receptors. The compound exhibits robust stability under standard bench conditions and integrates readily into synthetic sequences via electrophilic substitution or metal-catalyzed coupling reactions.

Application

3-Phenoxypyridine serves as a versatile building block in medicinal chemistry and materials science, offering a robust heteroaromatic scaffold with enhanced solubility and metabolic stability. Its phenoxyl group enables direct functionalization or coupling reactions, while the pyridine nitrogen provides a site for metal coordination or hydrogen bonding. The compound exhibits good bench stability and is compatible with standard cross-coupling and electrophilic substitution protocols, facilitating efficient synthesis of complex molecular architectures.

Synthesis

  • Route1

    References

    • Jalalian, Nazli; Petersen, Tue B.; Olofsson, Berit Chemistry--A European Journal, 2012 , vol. 18, # 44 p. 14140 - 14149,10
  • Route2
    • In-stock
      3-Hydroxypyridine|CS-W009147
      109-00-2
    • null|null
      108-86-1
    • ~7%
    • In-stock
      3-Phenoxypyridine|CS-0060564
      2176-45-6

    References

    • OXAGEN LIMITED Patent: WO2005/40112 A1, 2005 ; Location in patent: Page/Page column 62-63 ; WO 2005/040112 A1
  • Route3
    • In-stock
      3-Bromopyridine|CS-0008362
      626-55-1
    • null|null
      108-95-2
    • ~94%
    • In-stock
      3-Phenoxypyridine|CS-0060564
      2176-45-6

    References

    • Yang, Shuliang; Wu, Cunqi; Zhou, Hua; Yang, Yanqin; Zhao, Yongxia; Wang, Chenxu; Yang, Wei; Xu, Jingwei Advanced Synthesis and Catalysis, 2013 , vol. 355, # 1 p. 53 - 58

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302
Precautionary Statements : P264-P270-P330-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

  • TPSA   22.12
  • LogP   2.8739
  • H_Acceptors   2
  • H_Donors   0
  • Rotatable_Bonds   2

Other Classifications

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • 3-Phenoxypyridine sigma3-Phenoxypyridine manufacturer3-Phenoxypyridine price3-Phenoxypyridine structure3-Phenoxypyridine SDSbuy 3-Phenoxypyridine3-Phenoxypyridine supplier3-Phenoxypyridine uses3-Phenoxypyridine molecular weightprice of 3-Phenoxypyridine3-Phenoxypyridine chemical name formula of 3-Phenoxypyridine
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label