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CS-W001157 4
Total: USD 88.00

N-Demethylricinine

  • CAS No. 21642-98-8

  • Cat. No. CS-D0769
  • Purity≥97%
  • MDL No.MFCD00975442

*For research and further manufacturing use only, not for direct human use.

N-Demethylricinine|CS-D0769

Structure of 21642-98-8

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General Information

  • CAS No. 21642-98-8
  • Cat. No. CS-D0769
  • Purity ≥97%
  • MDL No. MFCD00975442
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₆N₂O₂
  • Molecular Weight 150.13
  • Synonym(s) None
  • SMILES N#CC1=C(OC)C=CNC1=O

Description

N-Demethylricinine features a demethylated pyrrolidine core with enhanced polarity, enabling improved solubility in aqueous-organic mixtures. This structural modification increases metabolic stability while preserving the molecule’s capacity to engage biological targets through hydrogen bonding and π-stacking interactions.

Application

N-Demethylricinine serves as a key intermediate in the synthesis of pyrrolidine-based alkaloids, enabling efficient access to core scaffolds through established reductive amination and cyclization protocols. Its bench-stable nature and tolerance to common functional groups facilitate straightforward incorporation into multi-step synthetic sequences, particularly in medicinal chemistry campaigns targeting CNS-active compounds.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS06
Signal Word : Danger
UN#: 3439
Class : 6.1
Packing Group : Ⅲ
Hazard Statements : H302+H312-H315-H319-H331-H335
Precautionary Statements : P264-P270-P330-P405-P501

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Computational Chemistry Data

  • TPSA   65.88
  • LogP   0.25518
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   1

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