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Methyl 1-aminocyclobutanecarboxylate

  • CAS No. 215597-35-6

  • Cat. No. CS-0183729
  • Purity≥98%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

Methyl 1-aminocyclobutanecarboxylate|CS-0183729

Structure of 215597-35-6

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General Information

  • CAS No. 215597-35-6
  • Cat. No. CS-0183729
  • Purity ≥98%
  • MDL No. None
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₁₁NO₂
  • Molecular Weight 129.16
  • Synonym(s) methyl 1-aminocyclobutane-1-carboxylate
  • SMILES COC(=O)C1(CCC1)N

Description

Methyl 1-aminocyclobutanecarboxylate features a strained cyclobutane ring with a pendant amine and ester functionality, enabling direct incorporation into peptide mimetics and bioactive scaffolds. The amine group facilitates derivatization under mild conditions, while the ester supports selective hydrolysis or coupling reactions. This compound exhibits excellent solubility in common organic solvents and stability under standard bench conditions, making it well-suited for synthetic and medicinal chemistry workflows.

Application

Methyl 1-aminocyclobutanecarboxylate serves as a versatile building block in medicinal chemistry, enabling efficient access to cyclobutane-containing scaffolds. Its amine and ester functionalities offer orthogonal reactivity for sequential transformations, including derivatization, amidation, or reduction. The compound exhibits good bench stability and is compatible with standard purification methods, facilitating integration into multi-step synthesis workflows for API development.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   52.32
  • LogP   0.0408
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   1

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