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CS-W001157 4
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Methyl 1-aminocyclobutanecarboxylate

  • CAS No. 215597-35-6

  • Cat. No. CS-0183729
  • Purity≥98%
  • MDL No.None
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    Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

    If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

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*For research and further manufacturing use only, not for direct human use.

Methyl 1-aminocyclobutanecarboxylate|CS-0183729

Structure of 215597-35-6

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Description

Methyl 1-aminocyclobutanecarboxylate features a strained cyclobutane ring with a pendant amine and ester functionality, enabling direct incorporation into peptide mimetics and bioactive scaffolds. The amine group facilitates derivatization under mild conditions, while the ester supports selective hydrolysis or coupling reactions. This compound exhibits excellent solubility in common organic solvents and stability under standard bench conditions, making it well-suited for synthetic and medicinal chemistry workflows.

Application

Methyl 1-aminocyclobutanecarboxylate serves as a versatile building block in medicinal chemistry, enabling efficient access to cyclobutane-containing scaffolds. Its amine and ester functionalities offer orthogonal reactivity for sequential transformations, including derivatization, amidation, or reduction. The compound exhibits good bench stability and is compatible with standard purification methods, facilitating integration into multi-step synthesis workflows for API development.

General Information

  • CAS No. 215597-35-6
  • Cat. No. CS-0183729
  • Purity ≥98%
  • MDL No. None
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₁₁NO₂
  • Molecular Weight 129.16
  • Synonym(s) methyl 1-aminocyclobutane-1-carboxylate
  • SMILES COC(=O)C1(CCC1)N

Computational Chemistry Data

  • TPSA   52.32
  • LogP   0.0408
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   1

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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