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CS-W001157 4
Total: USD 88.00

Naproxen impurity 5

  • CAS No. 21388-17-0

  • Cat. No. CS-0061463
  • Molecule weight186.25
  • Purity≥98%
  • MDL No.MFCD08704412

*For research and further manufacturing use only, not for direct human use.

Naproxen impurity 5|CS-0061463

Structure of 21388-17-0

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General Information

  • CAS No. 21388-17-0
  • Cat. No. CS-0061463
  • Purity ≥98%
  • MDL No. MFCD08704412
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₃H₁₄O
  • Molecular Weight 186.25
  • Synonym(s) None
  • SMILES O(C=1C=CC2=CC(=CC=C2C1)CC)C

Description

May be used for the preparation of phosphate buffered saline, and for the extraction and solubilization of proteins.

Application

2-Ethyl-6-methoxynaphthalene serves as a valuable building block in the synthesis of functionalized naphthalene scaffolds, offering predictable regiochemistry and enhanced solubility due to the methoxy group. Its ethyl substituent provides steric and electronic modulation, enabling use in palladium-catalyzed couplings and electrophilic aromatic substitutions. Bench-stable and readily purified by column chromatography, it facilitates efficient access to advanced intermediates for pharmaceutical and materials applications.

Synthesis

  • Route1
    • 2-Methoxynaphthalene Naproxen Impurity|CS-0229804
      93-04-9
    • ~71%
    • In-stock
      Naproxen impurity 5|CS-0061463
      21388-17-0

    References

    • Amoco Corporation Patent: US5235115 A1, 1993 ;
  • Route2
    • 2-Acetyl-6-methoxynaphthalene|CS-0229632
      3900-45-6
    • ~%
    • In-stock
      Naproxen impurity 5|CS-0061463
      21388-17-0

    References

    • Journal of Organic Chemistry, , vol. 22, p. 912
  • Route3
    • null|null
      1016160-94-3
    • null|null
      75-16-1
    • ~98%
    • In-stock
      Naproxen impurity 5|CS-0061463
      21388-17-0

    References

    • Guan, Bing-Tao; Xiang, Shi-Kai; Wang, Bi-Qin; Sun, Zuo-Peng; Wang, Yang; Zhao, Ke-Qing; Shi, Zhang-Jie Journal of the American Chemical Society, 2008 , vol. 130, # 11 p. 3268 - 3269

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302+H312+H332-H413
Precautionary Statements : P261-P264-P270-P271-P273-P280-P302+P352-P304+P340-P330-P362+P364-P501

Quality Control

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Computational Chemistry Data

  • TPSA   9.23
  • LogP   3.4108
  • H_Acceptors   1
  • H_Donors   0
  • Rotatable_Bonds   2

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