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Structure of 213598-05-1
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3-(2,2,2-Trifluoroacetyl)benzoic acid features a trifluoromethyl ketone group positioned ortho to a carboxylic acid, delivering enhanced electrophilicity and stability. This electron-deficient aryl ketone integrates readily into synthetic transformations requiring high reactivity under mild conditions. The compound exhibits excellent bench stability and solubility in common organic solvents, facilitating efficient use in pharmaceutical intermediates and complex molecule assembly.
3-(2,2,2-Trifluoroacetyl)benzoic acid serves as a versatile building block in medicinal and synthetic chemistry, enabling efficient access to fluorinated aromatic systems. The trifluoromethyl ketone moiety exhibits enhanced electrophilicity and metabolic stability, facilitating downstream transformations such as nucleophilic additions, condensations, and cyclizations. Its bench-stable nature and compatibility with common reaction conditions make it well-suited for modular synthesis of bioactive scaffolds and API intermediates.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: