Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

2-(Pyridin-4-yl)-1,3-thiazole-4-carboxylic acid

  • CAS No. 21278-86-4

  • Cat. No. CS-0204242
  • Purity≥98%
  • MDL No.MFCD00171745

*For research and further manufacturing use only, not for direct human use.

2-(Pyridin-4-yl)-1,3-thiazole-4-carboxylic acid|CS-0204242

Structure of 21278-86-4

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

General Information

  • CAS No. 21278-86-4
  • Cat. No. CS-0204242
  • Purity ≥98%
  • MDL No. MFCD00171745
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₆N₂O₂S
  • Molecular Weight 206.22
  • Synonym(s) 2-(4-Pyridyl)thiazole-4-carboxylic acid
  • SMILES O=C(O)C=1N=C(SC1)C=2C=CN=CC2

Description

t-Boc-N-amido-PEG4-CH2CO2H is a PEG linker containing a terminal carboxylic acid and Boc-protected amino group. The hydrophilic PEG spacer increases solubility in aqueous media. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. The Boc group can be deprotected under mild acidic conditions to form the free amine.

Synthesis

  • Route1
    • Ethyl 2-(pyridin-4-yl)thiazole-4-carboxylate|CS-0197005
      21278-85-3
    • ~73%
    • 2-(Pyridin-4-yl)-1,3-thiazole-4-carboxylic acid|CS-0204242
      21278-86-4

    References

    • Bioorganic and Medicinal Chemistry, , vol. 15, # 20 p. 6574 - 6595
  • Route2

    References

    • WO2004/41813 A1, ; Page 111 ; WO 2004/041813 A1
  • Route3

    References

    • Justus Liebigs Annalen der Chemie, , vol. 717, p. 148 - 153

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

  • TPSA   63.08
  • LogP   1.9033
  • H_Acceptors   4
  • H_Donors   1
  • Rotatable_Bonds   2

Other Classifications

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • 21278-86-4 sigma21278-86-4 manufacturer21278-86-4 price21278-86-4 structure21278-86-4 SDSbuy 21278-86-421278-86-4 supplier21278-86-4 uses21278-86-4 molecular weightprice of 21278-86-421278-86-4 chemical name formula of 21278-86-4
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label