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CS-W001157 4
Total: USD 88.00

(2S,6S)-1,2,6-Trimethylpiperazine dihydrochloride

  • CAS No. 2126143-60-8

  • Cat. No. CS-0053400
  • Purity≥95%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

(2S,6S)-1,2,6-Trimethylpiperazine dihydrochloride|CS-0053400

Structure of 2126143-60-8

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General Information

  • CAS No. 2126143-60-8
  • Cat. No. CS-0053400
  • Purity ≥95%
  • MDL No. None
  • Storage 4°C, sealed storage, away from moisture
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₁₈Cl₂N₂
  • Molecular Weight 201.14
  • Synonym(s) None
  • SMILES Cl.Cl.C[C@H]1CNC[C@H](C)N1C

Description

This bench-stable, moisture-tolerant piperazine derivative features a rigid, chiral scaffold ideal for asymmetric synthesis. The 1,2,6-trimethyl substitution pattern enhances solubility and steric control, enabling efficient incorporation into catalytic systems and bioactive molecule scaffolds under standard conditions.

Application

(2S,6S)-1,2,6-Trimethylpiperazine dihydrochloride serves as a chiral building block for medicinal chemistry applications, offering defined stereochemistry and enhanced solubility due to the dihydrochloride salt form. Its tertiary amine functionality enables efficient derivatization and facilitates incorporation into bioactive scaffolds. The molecule exhibits bench stability and compatibility with standard purification methods, supporting its use in iterative synthesis workflows.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   15.27
  • LogP   1.142
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   0

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