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CS-W001157 4
Total: USD 88.00

2-Acetyl-6-methoxypyridine

  • CAS No. 21190-93-2

  • Cat. No. CS-W008394
  • Purity≥98%
  • MDL No.MFCD08276836

*For research and further manufacturing use only, not for direct human use.

2-Acetyl-6-methoxypyridine|CS-W008394

Structure of 21190-93-2

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General Information

  • CAS No. 21190-93-2
  • Cat. No. CS-W008394
  • Purity ≥98%
  • MDL No. MFCD08276836
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₉NO₂
  • Molecular Weight 151.16
  • Synonym(s) 2-ACETYL-6-METHOXYPYRIDINE 97
  • SMILES COC1=CC=CC(=N1)C(C)=O

Description

2-Acetyl-6-methoxypyridine features a pyridine core functionalized with acetyl and methoxy groups at the 2- and 6-positions, respectively. This electron-deficient heterocycle serves as a key scaffold in synthetic routes to bioactive molecules, offering enhanced solubility and stability under standard reaction conditions.

Application

2-Acetyl-6-methoxypyridine serves as a versatile heterocyclic building block in medicinal chemistry, enabling efficient access to pyridine-based scaffolds through standard functional group transformations. Its acetyl and methoxy groups provide orthogonal reactivity for selective derivatization, while the molecule exhibits excellent bench stability and ease of purification. Functions as a key intermediate in the synthesis of bioactive compounds and pharmaceutical candidates.

Synthesis

  • Route1
    • null|null
      1628-89-3
    • null|null
      75-36-5
    • ~93%
    • In-stock
      2-Acetyl-6-methoxypyridine|CS-W008394
      21190-93-2

    References

    • Rajendar Reddy; Rajanna; Uppalaiah Tetrahedron Letters, 2013 , vol. 54, # 26 p. 3431 - 3436
  • Route2
    • null|null
      107465-29-2
    • ~61%
    • In-stock
      2-Acetyl-6-methoxypyridine|CS-W008394
      21190-93-2

    References

    • Abarca, Belen; Mojarred, Fatemeh; Jones, Gurnos; Phillips, Caroline; NG, Nadine; Wastling, Jonathan Tetrahedron, 1988 , vol. 44, # 10 p. 3005 - 3014
  • Route3
    • null|null
      107465-23-6
    • ~%
    • In-stock
      2-Acetyl-6-methoxypyridine|CS-W008394
      21190-93-2

    References

    • Tetrahedron Letters, , vol. 27, # 30 p. 3543 - 3546

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P302+P352

Quality Control

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Computational Chemistry Data

  • TPSA   39.19
  • LogP   1.2928
  • H_Acceptors   3
  • H_Donors   0
  • Rotatable_Bonds   2

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