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CS-W001157 4
Total: USD 88.00

N-Ethyltetrahydro-2H-pyran-4-amine

  • CAS No. 211814-15-2

  • Cat. No. CS-0040480
  • Purity≥96%
  • MDL No.MFCD06658446

*For research and further manufacturing use only, not for direct human use.

N-Ethyltetrahydro-2H-pyran-4-amine|CS-0040480

Structure of 211814-15-2

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General Information

  • CAS No. 211814-15-2
  • Cat. No. CS-0040480
  • Purity ≥96%
  • MDL No. MFCD06658446
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₁₅NO
  • Molecular Weight 129.20
  • Synonym(s) N-Ethyltetrahydropyran-4-amine
  • SMILES CCNC1CCOCC1

Description

N-Ethyltetrahydro-2H-pyran-4-amine features a saturated pyran ring with a primary amine at the 4-position and an ethyl substituent on nitrogen, delivering enhanced solubility and stability in polar solvents. This scaffold integrates seamlessly into bioactive molecule design, particularly for targeted drug discovery applications requiring flexible, electron-rich heterocycles.

Application

N-Ethyltetrahydro-2H-pyran-4-amine serves as a versatile bifunctional building block in medicinal chemistry, combining a secondary amine with a tetrahydropyran ring for enhanced metabolic stability. Its structure facilitates hydrogen bonding and conformational restraint, enabling efficient incorporation into bioactive scaffolds. The compound exhibits excellent bench stability, tolerates diverse reaction conditions, and simplifies purification due to its well-defined polarity profile—ideal for modular synthesis of pharmaceutical intermediates and target-oriented libraries.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   21.26
  • LogP   0.7749
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   2

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