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CS-W001157 4
Total: USD 88.00

1,1,1,5,5,5-Hexamethyl-3-phenyl-3-((trimethylsilyl)oxy)trisiloxane

  • CAS No. 2116-84-9

  • Cat. No. CS-0186280
  • Purity≥98%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

1,1,1,5,5,5-Hexamethyl-3-phenyl-3-((trimethylsilyl)oxy)trisiloxane|CS-0186280

Structure of 2116-84-9

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General Information

  • CAS No. 2116-84-9
  • Cat. No. CS-0186280
  • Purity ≥98%
  • MDL No. None
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₅H₃₂O₃Si₄
  • Molecular Weight 372.75
  • Synonym(s) Trisiloxane, 1,1,1,5,5,5-hexamethyl-3-phenyl-3-((trimethylsilyl)oxy)-
  • SMILES C[Si](C)(C)O[Si](C1=CC=CC=C1)(O[Si](C)(C)C)O[Si](C)(C)C

Description

This trisiloxane features a bulky, electron-rich framework with six methyl groups and a phenyl substituent, enhancing steric protection and thermal stability. The trimethylsilyl ether moiety provides moisture tolerance and facilitates safe handling. This structure enables straightforward incorporation into silane-based functionalization protocols without requiring stringent anhydrous conditions.

Application

1,1,1,5,5,5-Hexamethyl-3-phenyl-3-((trimethylsilyl)oxy)trisiloxane serves as a stable, bench-ready silylating agent that facilitates efficient O-silylation of alcohols and phenols under mild conditions. Its bulky trimethylsilyl and phenyl substituents confer enhanced stability and low reactivity toward protic impurities, enabling clean transformations with minimal side products. The reagent functions effectively in protecting group strategies and enables straightforward purification due to its volatility and compatibility with standard chromatographic protocols.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319
Precautionary Statements : P264-P280-P302+P352-P362+P364

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Computational Chemistry Data

  • TPSA   27.69
  • LogP   4.387
  • H_Acceptors   3
  • H_Donors   0
  • Rotatable_Bonds   7

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