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CS-W001157 4
Total: USD 88.00

5,7-Dihydroxy-4-methylcoumarin

  • CAS No. 2107-76-8

  • Cat. No. CS-0032108
  • Purity≥95%
  • MDL No.MFCD00016966

*For research and further manufacturing use only, not for direct human use.

5,7-Dihydroxy-4-methylcoumarin|CS-0032108

Structure of 2107-76-8

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General Information

  • CAS No. 2107-76-8
  • Cat. No. CS-0032108
  • Purity ≥95%
  • MDL No. MFCD00016966
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₀H₈O₄
  • Molecular Weight 192.17
  • Synonym(s) None
  • SMILES O=C1C=C(C)C2=C(O)C=C(O)C=C2O1

Description

5,7-Dihydroxy-4-methylcoumarin can be obtained by reacting phloroglucinol and ethylacetoacetate via Pechmann condensation in the presence of sulfuric acid.5,7-Dihydroxy-4-methylcoumarin may be used in the synthesis of pyrano[2,3-h]coumarin derivatives and 5,7-dihydroxy-8-formyl-4-methylcoumarin.

Synthesis

  • Route1
    • null|null
      108-73-6
    • In-stock
      Methyl acetylacetate|CS-0017265
      105-45-3
    • ~99%
    • In-stock
      5,7-Dihydroxy-4-methylcoumarin|CS-0032108
      2107-76-8

    References

    • Sharghi, Hashem; Jokar, Mahboubeh Heterocycles, 2007 , vol. 71, # 12 p. 2721 - 2733
  • Route2
    • null|null
      108-73-6
    • ~67%
    • In-stock
      5,7-Dihydroxy-4-methylcoumarin|CS-0032108
      2107-76-8

    References

    • Council of Scientific and Industrial Research Patent: US6716996 B1, 2004 ; Location in patent: Page column 8 ;
  • Route3
    • null|null
      108-73-6
    • In-stock
      Ethyl acetoacetate|CS-0016216
      141-97-9
    • ~99%
    • In-stock
      5,7-Dihydroxy-4-methylcoumarin|CS-0032108
      2107-76-8

    References

    • Parhami, Abolfath; Zare, Abdolkarim; Nikrooz, Marzieh; Khalafi-Nezhad, Ali; Haghighi, Saghar Mowlazadeh; Bargebid, Rahele; Moosavi-Zare, Ahmad Reza ARKIVOC (Gainesville, FL, United States), 2012 , vol. 2012, # 9 p. 111 - 121,11

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302
Precautionary Statements : P264-P270-P330-P501

Quality Control

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Computational Chemistry Data

  • TPSA   70.67
  • LogP   1.51262
  • H_Acceptors   4
  • H_Donors   2
  • Rotatable_Bonds   0

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