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CS-W001157 4
Total: USD 88.00

Methoxsalen

  • CAS No. 298-81-7

  • Cat. No. CS-1983
  • Purity≥98%
  • MDL No.MFCD00005009

*For research and further manufacturing use only, not for direct human use.

Methoxsalen|CS-1983

Structure of 298-81-7

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General Information

  • CAS No. 298-81-7
  • Cat. No. CS-1983
  • Purity ≥98%
  • MDL No. MFCD00005009
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₂H₈O₄
  • Molecular Weight None
  • Synonym(s) 8-Methoxypsoralen; Xanthotoxin; 8-MOP
  • SMILES O=C1OC(C(C=C1)=C2)=C(OC)C3=C2C=CO3

Description

.

Application

Methoxsalen serves as a well-established photosensitizer and prenylated coumarin derivative, enabling efficient [2+2] cycloaddition reactions upon UV-A irradiation. It functions as a key building block in the synthesis of bioactive heterocycles and DNA crosslinking agents, offering high bench stability and predictable reactivity in photochemical transformations. Its functional group tolerance facilitates integration into complex molecular architectures.

Synthesis

  • Route1

    References

    • Jain; Srivastava Journal of the Indian Chemical Society, 1991 , vol. 68, # 8 p. 452 - 454
  • Route2
    • null|null
      160778-32-5
    • ~20%
    • In-stock
      Methoxsalen|CS-1983
      298-81-7
    • null|null
      160778-33-6

    References

    • Tetrahedron Letters, , vol. 35, # 51 p. 9617 - 9618
  • Route3
    • null|null
      66510-32-5
    • ~%
    • In-stock
      Methoxsalen|CS-1983
      298-81-7

    References

    • US4130568 A1, ;

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07,GHS08
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H317-H341-H351
Precautionary Statements : P261-P264-P270-P272-P280-P302+P352-P330-P362+P364-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   52.58
  • LogP   2.5478
  • H_Acceptors   4
  • H_Donors   0
  • Rotatable_Bonds   1

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