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CS-W001157 4
Total: USD 88.00

3-(3,4-Dimethoxyphenyl)propanoic acid

  • CAS No. 2107-70-2

  • Cat. No. CS-W008790
  • Purity≥98%
  • MDL No.MFCD00002774

*For research and further manufacturing use only, not for direct human use.

3-(3,4-Dimethoxyphenyl)propanoic acid|CS-W008790

Structure of 2107-70-2

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General Information

  • CAS No. 2107-70-2
  • Cat. No. CS-W008790
  • Purity ≥98%
  • MDL No. MFCD00002774
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₁H₁₄O₄
  • Molecular Weight 210.23
  • Synonym(s) None
  • SMILES O=C(O)CCC1=CC=C(OC)C(OC)=C1

Description

This 3-(3,4-dimethoxyphenyl)propanoic acid features a benzene ring bearing two methoxy groups at the meta and para positions, delivering enhanced solubility and electron density. The propionic acid side chain enables direct coupling in peptide synthesis or conjugation workflows. Designed for robust performance under standard bench conditions, this compound integrates seamlessly into complex molecular architectures requiring aromatic stability and polar functionality.

Application

3-(3,4-Dimethoxyphenyl)propanoic acid serves as a versatile building block for bioactive molecule synthesis, offering a rigidified aromatic spacer with two methoxy groups that enhance solubility and modulate electronic properties. The carboxylic acid functionality enables straightforward derivatization via esterification, amidation, or coupling reactions. Its stability under standard bench conditions and compatibility with diverse reaction protocols make it well-suited for medicinal chemistry campaigns targeting CNS agents and kinase inhibitors.

Synthesis

  • Route1

    References

    • Sharma; Rathee, Raman Journal of the Indian Chemical Society, 2005 , vol. 82, # 10 p. 938 - 939
  • Route2

    References

    • Cueva, Juan Pablo; Nichols, David E. Synthesis, 2009 , # 5 p. 715 - 720
  • Route3
    • null|null
      20583-78-2
    • ~%
    • In-stock
      3-(3,4-Dimethoxyphenyl)propanoic acid|CS-W008790
      2107-70-2

    References

    • Journal of the Chemical Society, , vol. 91, p. 1079

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   55.76
  • LogP   1.721
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   5

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