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Structure of 210691-38-6
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This sulfonyl chloride features a trifluoromethylated acetyl group fused to an indoline scaffold, delivering enhanced reactivity and stability. The electron-deficient sulfonyl chloride moiety enables efficient coupling in amide bond formation, while the aromatic indoline core provides structural rigidity. Ideal for constructing bioactive molecules in medicinal chemistry workflows under standard conditions.
1-(2,2,2-Trifluoroacetyl)indoline-5-sulfonyl chloride serves as a versatile building block for the synthesis of sulfonamide-containing heterocycles, enabling efficient construction of indoline-based scaffolds with enhanced metabolic stability. The trifluoroacetyl group provides orthogonal reactivity, while the sulfonyl chloride moiety facilitates direct coupling with amines under mild conditions. Its bench-stable nature and compatibility with diverse functional groups make it well-suited for iterative synthesis in medicinal chemistry workflows.
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GHS Pictogram :
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GHS No : GHS05
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Signal Word : Danger
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UN#: 3261
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Class : 8
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Packing Group : Ⅱ
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Hazard Statements : H290-H314
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Precautionary Statements : P234-P260-P264-P280-P301+P330+P331-P304+P340-P363-P390-P405-P406-P501
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Lot numbers can be found on the outside label of a product: