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CS-W001157 4
Total: USD 88.00

5-Chloro-2-fluoroaniline

  • CAS No. 2106-05-0

  • Cat. No. CS-W010995
  • Purity≥98%
  • MDL No.MFCD00069416

*For research and further manufacturing use only, not for direct human use.

5-Chloro-2-fluoroaniline|CS-W010995

Structure of 2106-05-0

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General Information

  • CAS No. 2106-05-0
  • Cat. No. CS-W010995
  • Purity ≥98%
  • MDL No. MFCD00069416
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₅ClFN
  • Molecular Weight 145.56
  • Synonym(s) 5-CHLORO-2-FLUOROPHENYLAMINE
  • SMILES NC1=CC(Cl)=CC=C1F

Description

5-Chlorobenzo[b]thiophene is used as pharmaceutical intermediate.

Application

5-Chloro-2-fluoroaniline serves as a valuable building block in medicinal chemistry and agrochemical synthesis, enabling direct incorporation of fluorinated and chlorinated aromatic motifs. Its ortho-fluoro substitution enhances metabolic stability and modulates electronic properties, while the primary amine facilitates standard coupling reactions. The compound exhibits good bench stability and compatibility with common protecting groups, facilitating efficient downstream functionalization in multi-step syntheses.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362-P405-P501

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Computational Chemistry Data

  • TPSA   26.02
  • LogP   2.0613
  • H_Acceptors   1
  • H_Donors   1
  • Rotatable_Bonds   0

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