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(R)-7-Fluoro-2,3-dihydrobenzofuran-3-amine hydrochloride

  • CAS No. 2102410-16-0

  • Cat. No. CS-0196998
  • Purity≥97%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

(R)-7-Fluoro-2,3-dihydrobenzofuran-3-amine hydrochloride|CS-0196998

Structure of 2102410-16-0

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General Information

  • CAS No. 2102410-16-0
  • Cat. No. CS-0196998
  • Purity ≥97%
  • MDL No. None
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₉ClFNO
  • Molecular Weight 189.61
  • Synonym(s) (3R)-7-FLUORO-2,3-DIHYDRO-1-BENZOFURAN-3-AMINE Hydrogen chloride
  • SMILES O1C[C@@H](C=2C1=C(C=CC2)F)N.Cl

Description

(R)-7-Fluoro-2,3-dihydrobenzofuran-3-amine hydrochloride features a chiral benzofuran scaffold with a fluorinated aryl moiety and primary amine functionality. This bench-stable salt integrates readily into asymmetric synthesis workflows, offering enhanced solubility and predictable reactivity in medicinal chemistry applications.

Application

(R)-7-Fluoro-2,3-dihydrobenzofuran-3-amine hydrochloride serves as a valuable chiral building block in medicinal chemistry, enabling efficient access to fluorinated heterocyclic scaffolds. Its bench-stable hydrochloride salt form facilitates handling and purification, while the pendant amine group supports diverse functionalization via standard coupling and reductive amination protocols. The stereochemically defined (R)-configuration ensures consistent biological activity in target-directed synthesis.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P280-P302+P352

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Computational Chemistry Data

  • TPSA   35.25
  • LogP   1.6397
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   0

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