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CS-W001157 4
Total: USD 88.00

2,6-Dibromo-3,5-difluoropyridine

  • CAS No. 210169-13-4

  • Cat. No. CS-0146040
  • Purity≥97%
  • MDL No.MFCD21603841

*For research and further manufacturing use only, not for direct human use.

2,6-Dibromo-3,5-difluoropyridine|CS-0146040

Structure of 210169-13-4

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General Information

  • CAS No. 210169-13-4
  • Cat. No. CS-0146040
  • Purity ≥97%
  • MDL No. MFCD21603841
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₅HBr₂F₂N
  • Molecular Weight 272.87
  • Synonym(s) pyridine,2,6-dibromo-3,5-difluoro
  • SMILES FC1=C(Br)N=C(Br)C(F)=C1

Description

2,6-Dibromo-3,5-difluoropyridine features a highly electron-deficient pyridine core stabilized by orthogonal halogen substituents. This configuration enables selective cross-coupling reactions under mild conditions, facilitating efficient access to functionalized heteroaromatic scaffolds in medicinal chemistry and materials science.

Application

2,6-Dibromo-3,5-difluoropyridine serves as a versatile building block for the synthesis of fluorinated heterocycles and pharmaceutical intermediates. Its ortho-bromine substituents enable efficient palladium-catalyzed cross-coupling reactions, while the meta-fluorine atoms offer complementary reactivity in nucleophilic substitution processes. The molecule exhibits excellent bench stability and facilitates modular construction of complex scaffolds with high functional group tolerance.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   12.89
  • LogP   2.8848
  • H_Acceptors   1
  • H_Donors   0
  • Rotatable_Bonds   0

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