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Methyl 2-(2,2,2-trifluoroacetamido)imidazo[1,2-a]pyridine-6-carboxylate

  • CAS No. 209971-50-6

  • Cat. No. CS-0449828
  • Molecule weight287.19
  • Purity≥98%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

Methyl 2-(2,2,2-trifluoroacetamido)imidazo[1,2-a]pyridine-6-carboxylate|CS-0449828

Structure of 209971-50-6

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General Information

  • CAS No. 209971-50-6
  • Cat. No. CS-0449828
  • Purity ≥98%
  • MDL No. None
  • Storage Sealed in dry,2-8℃
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₁H₈F₃N₃O₃
  • Molecular Weight 287.19
  • Synonym(s) METHYL 2-(2,2,2-TRIFLUORO-ACETYLAMINO)-IMIDAZO[1,2-A]PYRIDINE-6-CARBOXYLATE
  • SMILES COC(C1=CN2C=C(NC(C(F)(F)F)=O)N=C2C=C1)=O

Synthesis

  • Route1
    • null|null
      1208250-24-1
    • null|null
      407-25-0
    • ~%
    • Methyl 2-(2,2,2-trifluoroacetamido)imidazo[1,2-a]pyridine-6-carboxylate|CS-0449828
      209971-50-6

    References

    • TAKEDA PHARMACEUTICAL COMPANY LIMITED; BRESSI, Jerome, C.; CHU, Shaosong; ERICKSON, Philip; KOMANDLA, Mallareddy; KWOK, Lily; LAWSON, John, D.; STAFFORD, Jeffrey, A.; WALLACE, Michael, B.; ZHANG, Zhiyuan; DAS, Sanjib Patent: WO2010/19899 A1, 2010 ; Location in patent: Page/Page column 126-127 ;
  • Route2
    • null|null
      407-25-0
    • null|null
      209971-47-1
    • ~47%
    • Methyl 2-(2,2,2-trifluoroacetamido)imidazo[1,2-a]pyridine-6-carboxylate|CS-0449828
      209971-50-6

    References

    • Hamdouchi, Chafiq; Sanchez, Concha; Ezquerra, Jesus Synthesis, 1998 , # 6 p. 867 - 872
  • Route3

    References

    • Hamdouchi, Chafiq; Sanchez, Concha; Ezquerra, Jesus Synthesis, 1998 , # 6 p. 867 - 872

Safety Information

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GHS Pictogram : N/A
GHS No : N/A
Signal Word : N/A
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : N/A
Precautionary Statements : N/A

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Computational Chemistry Data

  • TPSA   72.7
  • LogP   1.6217
  • H_Acceptors   5
  • H_Donors   1
  • Rotatable_Bonds   2

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