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CS-W001157 4
Total: USD 88.00

(2,6-Bis(benzyloxy)pyridin-3-yl)boronic acid

  • CAS No. 2096339-92-1

  • Cat. No. CS-0138569
  • Purity≥98%
  • MDL No.MFCD18434424

*For research and further manufacturing use only, not for direct human use.

(2,6-Bis(benzyloxy)pyridin-3-yl)boronic acid|CS-0138569

Structure of 2096339-92-1

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General Information

  • CAS No. 2096339-92-1
  • Cat. No. CS-0138569
  • Purity ≥98%
  • MDL No. MFCD18434424
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₉H₁₈BNO₄
  • Molecular Weight None
  • Synonym(s) FCD18434424
  • SMILES OB(C1=CC=C(OCC2=CC=CC=C2)N=C1OCC3=CC=CC=C3)O

Description

This boronate moiety features a pyridine core functionalized with two benzyloxy groups at the 2 and 6 positions, enhancing solubility and stability. The pendant boronic acid enables efficient Suzuki-Miyaura coupling under standard conditions, while the ortho-benzyloxy substituents offer steric protection and facilitate purification. Designed for streamlined synthesis in medicinal chemistry and materials science applications.

Application

(2,6-Bis(benzyloxy)pyridin-3-yl)boronic acid serves as a stable, bench-ready building block for Suzuki-Miyaura cross-coupling reactions. The pyridine core enables directed functionalization, while the benzyloxy groups provide orthogonal protection and enhanced solubility. Its robust boronic acid functionality facilitates reliable coupling with aryl halides under standard conditions, making it well-suited for constructing complex heterocyclic scaffolds in medicinal chemistry and materials synthesis.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P260-P264-P270-P271-P280-P301+P310-P302+P352-P304+P340-P305+P351+P338-P312-P330-P332+P313-P337+P313-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   71.81
  • LogP   1.9194
  • H_Acceptors   5
  • H_Donors   2
  • Rotatable_Bonds   7

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