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Potassium (3-(tert-butoxycarbonyl)-3-azabicyclo[3.1.0]hexan-1-yl)trifluoroborate

  • CAS No. 2095504-38-2

  • Cat. No. CS-0091531
  • Purity≥97%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

Potassium (3-(tert-butoxycarbonyl)-3-azabicyclo[3.1.0]hexan-1-yl)trifluoroborate|CS-0091531

Structure of 2095504-38-2

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General Information

  • CAS No. 2095504-38-2
  • Cat. No. CS-0091531
  • Purity ≥97%
  • MDL No. None
  • Storage 4°C, sealed storage, away from moisture
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₀H₁₆BF₃KNO₂
  • Molecular Weight 289.14
  • Synonym(s) None
  • SMILES F[B-](F)(F)C12C(CN(C(OC(C)(C)C)=O)C2)C1.[K+]

Description

Potassium (3-(tert-butoxycarbonyl)-3-azabicyclo[3.1.0]hexan-1-yl)trifluoroborate delivers a stable, bench-ready boronate handle for late-stage functionalization in synthetic and medicinal chemistry. The protected azabicyclic scaffold enables selective cross-coupling under mild conditions, combining enhanced solubility with predictable reactivity in diverse reaction environments.

Application

Potassium (3-(tert-butoxycarbonyl)-3-azabicyclo[3.1.0]hexan-1-yl)trifluoroborate serves as a stable, bench-ready boron building block for Suzuki-Miyaura coupling reactions. The Boc-protected azabicyclic scaffold enables efficient C–C bond formation under mild conditions, with excellent functional group tolerance and compatibility in complex molecule synthesis. Its robustness facilitates straightforward purification and integration into multi-step sequences, making it a practical reagent for constructing nitrogen-containing heterocyclic motifs in medicinal chemistry and natural product derivatization.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   29.54
  • LogP   -0.1512
  • H_Acceptors   2
  • H_Donors   0
  • Rotatable_Bonds   1

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