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(1S,2S)-2-Methylcyclopropanamine hydrochloride

  • CAS No. 2088414-03-1

  • Cat. No. CS-0214194
  • Purity≥95%
  • MDL No.MFCD30730496

*For research and further manufacturing use only, not for direct human use.

(1S,2S)-2-Methylcyclopropanamine hydrochloride|CS-0214194

Structure of 2088414-03-1

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General Information

  • CAS No. 2088414-03-1
  • Cat. No. CS-0214194
  • Purity ≥95%
  • MDL No. MFCD30730496
  • Storage Store at room temperature, keep dry and cool
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₄H₁₀ClN
  • Molecular Weight 107.58
  • Synonym(s) (1S,2S)-2-Methylcyclopropan-1-amine hydrochloride
  • SMILES C[C@@H]1[C@H](C1)N.Cl

Description

(1S,2S)-2-Methylcyclopropanamine hydrochloride is a stereochemically defined cyclopropane derivative featuring a chiral amine center. This bench-stable salt integrates readily into asymmetric synthesis and medicinal chemistry workflows, offering high enantioselectivity in catalytic transformations. The constrained ring system imparts rigidity, enhancing target binding affinity in bioactive molecule design.

Application

(1S,2S)-2-Methylcyclopropanamine hydrochloride serves as a conformationally constrained chiral amine building block, enabling stereoselective synthesis of bioactive molecules. Its rigid cyclopropane scaffold imparts enhanced metabolic stability and defined spatial orientation, facilitating efficient coupling in peptide mimetics and medicinal chemistry campaigns. The hydrochloride salt ensures excellent bench stability, solubility, and ease of handling during standard synthetic workflows.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   26.02
  • LogP   0.7753
  • H_Acceptors   1
  • H_Donors   1
  • Rotatable_Bonds   0

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