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CS-W001157 4
Total: USD 88.00

(S)-2-Amino-3,3-dimethylbutanoic acid

  • CAS No. 20859-02-3

  • Cat. No. CS-D0917
  • Purity≥98%
  • MDL No.MFCD00064218

*For research and further manufacturing use only, not for direct human use.

(S)-2-Amino-3,3-dimethylbutanoic acid|CS-D0917

Structure of 20859-02-3

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General Information

  • CAS No. 20859-02-3
  • Cat. No. CS-D0917
  • Purity ≥98%
  • MDL No. MFCD00064218
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₁₃NO₂
  • Molecular Weight 131.17
  • Synonym(s) None
  • SMILES N[C@@H](C(C)(C)C)C(O)=O

Description

(S)-2-Amino-3,3-dimethylbutanoic acid is a chiral, non-proteinogenic amino acid featuring a branched aliphatic side chain. This sterically hindered structure enhances metabolic stability and facilitates incorporation into peptide scaffolds requiring resistance to enzymatic degradation. The molecule displays favorable solubility in aqueous and polar organic media under standard conditions.

Synthesis

  • Route1
    • null|null
      202347-81-7
    • ~95%
    • In-stock
      (S)-2-Amino-3,3-dimethylbutanoic acid|CS-D0917
      20859-02-3

    References

    • Harwood, Laurence M.; Tyler, Simon N. G.; Anslow, A. Susan; MacGilp, Iain D.; Drew, Michael G. B. Tetrahedron Asymmetry, 1997 , vol. 8, # 24 p. 4007 - 4010
  • Route2

    References

    • Agosta, Eleonora; Caligiuri, Antonio; D'Arrigo, Paola; Servi, Stefano; Tessaro, Davide; Canevotti, Renato Tetrahedron Asymmetry, 2006 , vol. 17, # 13 p. 1995 - 1999
  • Route3

    References

    • Journal of the American Chemical Society, , vol. 114, # 5 p. 1906 - 1908

Safety Information

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GHS Pictogram : N/A
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UN#: N/A
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Hazard Statements : N/A
Precautionary Statements : N/A

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Computational Chemistry Data

  • TPSA   63.32
  • LogP   0.4444
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   1

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