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CS-W001157 4
Total: USD 88.00

(S,R,S)-AHPC-PEG4-NH2 (hydrochloride)

  • CAS No. 2064292-52-8

  • Cat. No. CS-7740
  • Purity≥98%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

(S,R,S)-AHPC-PEG4-NH2 (hydrochloride)|CS-7740

Structure of 2064292-52-8

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General Information

  • CAS No. 2064292-52-8
  • Cat. No. CS-7740
  • Purity ≥98%
  • MDL No. None
  • Storage 4°C, sealed storage, away from moisture
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₃₂H₅₀ClN₅O₈S
  • Molecular Weight 700.29
  • Synonym(s) VH032-PEG4-NH2 (hydrochloride); VHL Ligand-Linker Conjugates 4 (hydrochloride); E3 ligase Ligand-Linker Conjugates 7
  • SMILES O=C(N[C@@H](C(C)(C)C)C(N(C[C@H](O)C1)[C@@H]1C(NCC2=CC=C(C(SC=N3)=C3C)C=C2)=O)=O)COCCOCCOCCOCCN.Cl

Description

(S,R,S)-AHPC-PEG4-NH2 (hydrochloride) features a chiral AHPC core linked to a PEG4 spacer and primary amine terminus, enabling site-specific conjugation in bioconjugation workflows. The hydrochloride salt enhances solubility and stability under standard conditions, facilitating reliable use in peptide and protein labeling applications.

Application

(S,R,S)-AHPC-PEG4-NH₂ (hydrochloride) serves as a versatile bifunctional linker for peptide and biomolecule conjugation, enabling efficient coupling via amine-reactive chemistries. The PEG4 spacer provides enhanced solubility and reduced aggregation, while the chiral AHPC moiety facilitates site-specific attachment. Bench-stable and readily purified, it functions effectively in solid-phase synthesis and bioconjugation workflows.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   174.57
  • LogP   1.67432
  • H_Acceptors   11
  • H_Donors   4
  • Rotatable_Bonds   19

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