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CS-W001157 4
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2-(2,4-Difluorophenyl)-2,2-difluoroethan-1-amine hydrochloride

  • CAS No. 2060062-92-0

  • Cat. No. CS-0163388
  • Purity≥95%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

2-(2,4-Difluorophenyl)-2,2-difluoroethan-1-amine hydrochloride|CS-0163388

Structure of 2060062-92-0

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General Information

  • CAS No. 2060062-92-0
  • Cat. No. CS-0163388
  • Purity ≥95%
  • MDL No. None
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₈ClF₄N
  • Molecular Weight 229.60
  • Synonym(s) None
  • SMILES NCC(F)(C1=CC=C(F)C=C1F)F.[H]Cl

Description

This difluorophenyl-substituted ethanamine hydrochloride delivers a robust, moisture-tolerant scaffold for medicinal chemistry. The electron-deficient aryl moiety enhances metabolic stability, while the primary amine facilitates conjugation and derivatization under standard conditions.

Application

2-(2,4-Difluorophenyl)-2,2-difluoroethan-1-amine hydrochloride serves as a valuable building block in medicinal chemistry, enabling the construction of fluorinated aromatic amine scaffolds. Its difluoromethyl group enhances metabolic stability and modulates lipophilicity, while the amine functionality facilitates downstream derivatization via standard coupling reactions. The hydrochloride salt form ensures excellent bench stability and ease of handling, supporting reliable performance in multi-step synthesis workflows.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319
Precautionary Statements : P264-P280-P302+P352-P362+P364

Quality Control

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Computational Chemistry Data

  • TPSA   26.02
  • LogP   2.4371
  • H_Acceptors   1
  • H_Donors   1
  • Rotatable_Bonds   2

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