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CS-W001157 4
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5-Bromo-3-methyl-1H-pyrazolo[4,3-b]pyridine

  • CAS No. 2055840-60-1

  • Cat. No. CS-0197757
  • Purity≥97%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

5-Bromo-3-methyl-1H-pyrazolo[4,3-b]pyridine|CS-0197757

Structure of 2055840-60-1

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General Information

  • CAS No. 2055840-60-1
  • Cat. No. CS-0197757
  • Purity ≥97%
  • MDL No. None
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₆BrN₃
  • Molecular Weight 212.05
  • Synonym(s) None
  • SMILES BrC1=NC=2C(=NNC2C=C1)C

Description

5-Bromo-3-methyl-1H-pyrazolo[4,3-b]pyridine is a heterocyclic scaffold featuring a bromo substituent at the 5-position and a methyl group at the 3-position, enabling selective functionalization in transition metal-catalyzed cross-coupling reactions. This electron-deficient pyrazolopyridine core exhibits enhanced stability under standard reaction conditions and serves as a key building block for medicinal chemistry applications.

Application

5-Bromo-3-methyl-1H-pyrazolo[4,3-b]pyridine serves as a versatile heterocyclic building block for medicinal chemistry and materials science. Its bromine substituent enables palladium-catalyzed cross-coupling reactions, while the methyl group provides steric and electronic modulation. The fused pyrazolo[4,3-b]pyridine core offers enhanced stability and predictable reactivity in C–H functionalization and Suzuki-Miyaura coupling protocols. This compound functions effectively as a scaffold for targeted synthesis of bioactive molecules and advanced conjugated systems.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   41.57
  • LogP   2.02882
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   0

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