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CS-W001157 4
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2,5-Bis(2-methoxyethoxy)terephthalaldehyde

  • CAS No. 2053247-15-5

  • Cat. No. CS-0170771
  • Molecule weight282.29
  • Purity≥97%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

2,5-Bis(2-methoxyethoxy)terephthalaldehyde|CS-0170771

Structure of 2053247-15-5

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General Information

  • CAS No. 2053247-15-5
  • Cat. No. CS-0170771
  • Purity ≥97%
  • MDL No. None
  • Storage 4°C, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₄H₁₈O₆
  • Molecular Weight 282.29
  • Synonym(s) None
  • SMILES O=CC1=CC(OCCOC)=C(C=O)C=C1OCCOC

Description

2,5-Bis(2-methoxyethoxy)terephthalaldehyde features two methoxyethoxy substituents flanking a central aldehyde-functionalized terephthalate core. This electron-rich aromatic scaffold offers enhanced solubility in polar solvents and stability under standard bench conditions. The aldehyde groups enable straightforward conjugation in polymer synthesis and bioconjugation workflows, particularly where moisture tolerance and prolonged shelf life are required.

Application

2,5-Bis(2-methoxyethoxy)terephthalaldehyde serves as a versatile bifunctional aldehyde building block for the synthesis of polyaromatic scaffolds and functionalized ligands. Its ortho-dialdehyde functionality enables efficient condensation reactions with diamines and hydroxylamines, facilitating the construction of heterocyclic frameworks and macrocyclic architectures. The methoxyethoxy substituents enhance solubility and stability in polar solvents, while maintaining compatibility with standard protection/deprotection sequences. This compound is particularly useful in modular library synthesis and materials chemistry applications requiring robust, bench-stable aldehyde handles.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   71.06
  • LogP   1.362
  • H_Acceptors   6
  • H_Donors   0
  • Rotatable_Bonds   10

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