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CS-W001157 4
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1-(((Tert-butoxycarbonyl)amino)methyl)cyclopentane-1-carboxylic acid

  • CAS No. 204514-22-7

  • Cat. No. CS-0116195
  • Purity≥97%
  • MDL No.MFCD09264201

*For research and further manufacturing use only, not for direct human use.

1-(((Tert-butoxycarbonyl)amino)methyl)cyclopentane-1-carboxylic acid|CS-0116195

Structure of 204514-22-7

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General Information

  • CAS No. 204514-22-7
  • Cat. No. CS-0116195
  • Purity ≥97%
  • MDL No. MFCD09264201
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₂H₂₁NO₄
  • Molecular Weight 243.30
  • Synonym(s) 1-(((tert-Butoxycarbonyl)amino)methyl)cyclopentanecarboxylic acid
  • SMILES O=C(C1(CNC(OC(C)(C)C)=O)CCCC1)O

Description

This cyclopentane-based amino acid derivative features a tert-butoxycarbonyl-protected amine and a carboxylic acid group, enabling direct incorporation into peptide synthesis. The rigid cyclopentane scaffold provides conformational stability, while the Boc moiety ensures efficient protection during iterative coupling. This compound serves as a valuable building block for constrained peptidomimetics and bioactive molecule libraries.

Application

1-(((Tert-butoxycarbonyl)amino)methyl)cyclopentane-1-carboxylic acid serves as a versatile building block in medicinal chemistry, enabling the synthesis of cyclopentane-based peptidomimetics and bioactive scaffolds. The Boc-protected amine and carboxylic acid functionalities provide orthogonal reactivity for sequential coupling strategies. Its bench-stable nature and compatibility with standard peptide synthesis protocols facilitate efficient purification and scalability in API development workflows.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H332-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   75.63
  • LogP   2.1561
  • H_Acceptors   3
  • H_Donors   2
  • Rotatable_Bonds   3

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