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(R)-1-Ethylpiperidin-3-amine dihydrochloride

  • CAS No. 2031242-60-9

  • Cat. No. CS-0311909
  • Purity≥97%
  • MDL No.MFCD30345338

*For research and further manufacturing use only, not for direct human use.

(R)-1-Ethylpiperidin-3-amine dihydrochloride|CS-0311909

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General Information

  • CAS No. 2031242-60-9
  • Cat. No. CS-0311909
  • Purity ≥97%
  • MDL No. MFCD30345338
  • Storage 4°C, sealed storage, away from moisture and light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₁₈Cl₂N₂
  • Molecular Weight 201.14
  • Synonym(s) (3R)-1-ethylpiperidin-3-amine dihydrochloride
  • SMILES CCN1C[C@@H](CCC1)N.Cl.Cl

Description

(R)-1-Ethylpiperidin-3-amine dihydrochloride is a chiral amine scaffold featuring a stereodefined tertiary amine and a primary amine, enabling selective conjugation in medicinal chemistry. The dihydrochloride salt enhances solubility and stability under standard conditions, facilitating use in peptide coupling, catalyst design, and bioactive molecule synthesis.

Application

(R)-1-Ethylpiperidin-3-amine dihydrochloride serves as a versatile chiral building block in medicinal chemistry, enabling the synthesis of bioactive amine-containing scaffolds. Its well-defined stereochemistry and improved solubility facilitate efficient incorporation into drug candidates, particularly in kinase inhibitors and CNS-targeted therapeutics. The compound exhibits excellent bench stability and compatibility with standard coupling protocols, simplifying purification and downstream functionalization.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   29.26
  • LogP   1.273
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   1

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