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CS-W001157 4
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4-Nitro-2-amino-1-ethylbenzene

  • CAS No. 20191-74-6

  • Cat. No. CS-0012535
  • Purity≥96%
  • MDL No.MFCD00034056
  • HazMat Fee +

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    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

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*For research and further manufacturing use only, not for direct human use.

4-Nitro-2-amino-1-ethylbenzene|CS-0012535

Structure of 20191-74-6

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Description

4-Nitro-2-amino-1-ethylbenzene features a para-nitro group and ortho-amino functionality on an ethyl-substituted benzene ring, enabling dual reactivity in coupling and functionalization processes. This electron-deficient scaffold integrates readily into complex molecular architectures under standard conditions.

Application

4-Nitro-2-amino-1-ethylbenzene serves as a versatile building block for the synthesis of functionalized aromatic scaffolds, enabling direct access to substituted anilines and heterocycles via standard coupling and cyclization protocols. The ortho-amino and para-nitro groups offer complementary reactivity for sequential transformations, while the ethyl substituent enhances solubility and modulates electronic effects. Its bench-stable nature and compatibility with common reaction conditions facilitate efficient purification and integration into multi-step syntheses.

General Information

  • CAS No. 20191-74-6
  • Cat. No. CS-0012535
  • Purity ≥96%
  • MDL No. MFCD00034056
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₁₀N₂O₂
  • Molecular Weight 166.18
  • Synonym(s) Aniline, 2-ethyl-5-nitro- ; 2-Ethyl-5-nitroaniline; 2-Ethyl-5-nitrobenzenamine; Pazopanib Impurity 53
  • SMILES CCC1=CC=C([N+]([O-])=O)C=C1N

Computational Chemistry Data

  • TPSA   69.16
  • LogP   1.7394
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   2

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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