2-Bromo-1-chloro-4-fluorobenzene

Name: 2-Bromo-1-chloro-4-fluorobenzene
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 201849-15-2
Cat. No. CS-W002281
Purity≥98%
MDL No.MFCD00061120

HazMat Fee +

HazMat Fee

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

The shipment is processed through FedEx Ground under the Limited Quantity option.

Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

2-Bromo-1-chloro-4-fluorobenzene|CS-W002281

Structure of 201849-15-2

Size

Price

Quantity

* Please select Quantity before adding items.

Description

2-Bromo-1-chloro-4-fluorobenzene is a trifluorinated aromatic building block featuring complementary halogen handles for cross-coupling and functionalization. The ortho-chloro and para-fluoro substituents enable selective derivatization, while the bromine serves as a reactive anchor in palladium-catalyzed transformations. This electron-deficient scaffold supports efficient diversification in medicinal chemistry and materials synthesis under standard conditions.

Application

2-Bromo-1-chloro-4-fluorobenzene serves as a versatile building block in cross-coupling reactions, enabling the synthesis of substituted biaryls and functionalized heterocycles. Its orthogonal halogenation pattern provides predictable reactivity in Pd-catalyzed coupling protocols, with bromine typically reacting preferentially over chlorine. The compound exhibits excellent bench stability and facilitates straightforward purification, making it well-suited for scalable medicinal chemistry campaigns and API intermediate development.

General Information

CAS No. 201849-15-2
Cat. No. CS-W002281
Purity ≥98%
MDL No. MFCD00061120
Storage Store at room temperature
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₆H₃BrClF
Molecular Weight 209.44
Synonym(s) 3-BROMO-4-CHLOROFLUOROBENZENE
SMILES BrC1=C(Cl)C=CC(F)=C1

Computational Chemistry Data

TPSA 0
LogP 3.2416
H_Acceptors 0
H_Donors 0
Rotatable_Bonds 0

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Other Classifications

Building Blocks Functional Group Chloride

Building Blocks Functional Group Bromide

Building Blocks Skeleton Aromatic ring compounds Benzene compounds

Key Words

2-Bromo-1-chloro-4-fluorobenzene sigma2-Bromo-1-chloro-4-fluorobenzene manufacturer2-Bromo-1-chloro-4-fluorobenzene price2-Bromo-1-chloro-4-fluorobenzene structure2-Bromo-1-chloro-4-fluorobenzene SDSbuy 2-Bromo-1-chloro-4-fluorobenzene2-Bromo-1-chloro-4-fluorobenzene supplier2-Bromo-1-chloro-4-fluorobenzene uses2-Bromo-1-chloro-4-fluorobenzene molecular weightprice of 2-Bromo-1-chloro-4-fluorobenzene2-Bromo-1-chloro-4-fluorobenzene chemical name formula of 2-Bromo-1-chloro-4-fluorobenzene

Salutation:	*Country or Region:
*Applicant Name:	*Organization Name:
*Email Address:	Quantity:
CAS NO. :	Product Name:
Remarks:
Upload Pictures

CAS.No.		Product Name
Applicant Name *		Email Address *
Phone Number *		Organization Name*
Country or Region*		Quantity*
Remarks:

Product Name:
Cat. No.: .		CAS NO. :
Quantity:

2-Bromo-1-chloro-4-fluorobenzene

CAS No. 201849-15-2

Recommended Products