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Structure of 1000577-58-1
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1-Bromo-2,3-dichloro-5-fluorobenzene features a highly functionalized aromatic core with halogen substituents enabling precise cross-coupling and electrophilic substitution reactions. The strategic placement of bromine, chlorine, and fluorine atoms provides orthogonal reactivity for sequential derivatization. This electron-deficient scaffold delivers excellent stability under standard conditions and facilitates efficient incorporation into complex molecular architectures.
1-Bromo-2,3-dichloro-5-fluorobenzene serves as a versatile building block in medicinal chemistry and agrochemical synthesis, enabling palladium-catalyzed cross-coupling reactions due to its well-defined halogenation pattern. The strategic placement of bromine, chlorine, and fluorine substituents allows for sequential functionalization with high regioselectivity. Its bench-stable nature and compatibility with standard Suzuki, Stille, and Negishi coupling protocols make it ideal for constructing complex aromatic scaffolds in multi-step syntheses.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: