Fmoc-HoCit-OH

Name: Fmoc-HoCit-OH
Brand: ChemScene
Availability: InStock
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CAS No. 201485-17-8
Cat. No. CS-0187431
Purity≥97%
MDL No.None

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

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Structure of 201485-17-8

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General Information

CAS No. 201485-17-8
Cat. No. CS-0187431
Purity ≥97%
MDL No. None
Storage Store at room temperature
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₂₂H₂₅N₃O₅
Molecular Weight 411.45
Synonym(s) N6-(Aminocarbonyl)-N2-[(9H-Fluoren-9-Ylmethoxy)Carbonyl]-L-Lysine
SMILES NC(NCCCC[C@@H](C(O)=O)NC(OCC1C2=CC=CC=C2C3=CC=CC=C31)=O)=O

Description

Fmoc-HoCit-OH is a protected amino acid derivative featuring a hydroxy-ornithine scaffold with a C-terminal carboxylic acid. This reagent integrates readily into solid-phase peptide synthesis workflows, offering a stable, moisture-tolerant platform for incorporating ornithine analogs with enhanced solubility and controlled reactivity under standard conditions.

Application

Fmoc-HoCit-OH serves as a key building block for the synthesis of peptide-conjugated chelators and metal-binding scaffolds. Its ortho-hydroxybenzyl moiety enables efficient coordination to radiometals, while the Fmoc group facilitates standard solid-phase peptide synthesis. The compound exhibits excellent bench stability, ease of purification, and compatibility with diverse functional groups, making it ideal for constructing multifunctional bioconjugates in targeted radiotherapeutics and imaging agents.

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

Quality Control

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Computational Chemistry Data

TPSA 130.75
LogP 2.8169
H_Acceptors 4
H_Donors 4
Rotatable_Bonds 9

Other Classifications

Building Blocks Functional Group Urea

Building Blocks Skeleton Chiral compounds Chiral Building Blocks

Life Science Amino Acids and their Derivatives Non-protein amino acids

Chemical Biology Peptide Chemistry Amine Protection

Chemical Biology Peptide Chemistry Unnatural Amino Acid Derivatives

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Fmoc-HoCit-OH

CAS No. 201485-17-8

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