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CS-W001157 4
Total: USD 88.00

(S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3,3-diphenylpropanoic acid

  • CAS No. 201484-50-6

  • Cat. No. CS-W011553
  • Purity≥98%
  • MDL No.MFCD00672337

*For research and further manufacturing use only, not for direct human use.

(S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3,3-diphenylpropanoic acid|CS-W011553

Structure of 201484-50-6

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General Information

  • CAS No. 201484-50-6
  • Cat. No. CS-W011553
  • Purity ≥98%
  • MDL No. MFCD00672337
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₃₀H₂₅NO₄
  • Molecular Weight 463.52
  • Synonym(s) None
  • SMILES O=C([C@H](C(C1=CC=CC=C1)C2=CC=CC=C2)NC(OCC3C4=C(C=CC=C4)C5=C3C=CC=C5)=O)O

Description

(S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3,3-diphenylpropanoic acid is a chiral building block featuring a sterically hindered diphenylpropanoic acid core protected with a fluorenylmethoxycarbonyl (Fmoc) group. This combination enables stable incorporation into peptide synthesis workflows while maintaining high enantiomeric purity and compatibility with standard coupling conditions.

Application

(S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3,3-diphenylpropanoic acid serves as a robust chiral building block for peptide synthesis, leveraging the orthogonal stability of the Fmoc group. Its diphenyl-substituted β-carbon enhances steric definition and conformational rigidity, enabling precise stereocontrol in coupling reactions. The compound exhibits excellent bench stability, facilitates straightforward purification via standard chromatography, and functions effectively in both solution-phase and solid-phase workflows.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   75.63
  • LogP   5.8104
  • H_Acceptors   3
  • H_Donors   2
  • Rotatable_Bonds   7

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