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CS-W001157 4
Total: USD 88.00

(3-(Benzyloxy)cyclobutane-1,1-diyl)dimethanol

  • CAS No. 20061-24-9

  • Cat. No. CS-0057134
  • Molecule weight222.28
  • Purity≥97%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

(3-(Benzyloxy)cyclobutane-1,1-diyl)dimethanol|CS-0057134

Structure of 20061-24-9

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General Information

  • CAS No. 20061-24-9
  • Cat. No. CS-0057134
  • Purity ≥97%
  • MDL No. None
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₃H₁₈O₃
  • Molecular Weight 222.28
  • Synonym(s) [3-(benzyloxy)-1-(hydroxymethyl)cyclobutyl]methanol
  • SMILES OCC1(CO)CC(OCC2=CC=CC=C2)C1

Description

This bench-stable diol features a rigid cyclobutane core flanked by benzyl-protected hydroxyl groups, enabling selective deprotection and integration into complex molecular architectures. Its orthogonal functionality supports sequential derivatization in synthetic workflows.

Application

(3-(Benzyloxy)cyclobutane-1,1-diyl)dimethanol serves as a versatile diol building block for the synthesis of constrained cyclic scaffolds. Its benzyloxymethyl groups provide orthogonal protection and facilitate selective transformations, while the cyclobutane core offers rigidity beneficial in medicinal chemistry. The molecule exhibits excellent bench stability and enables straightforward purification, making it well-suited for multi-step syntheses requiring functional group tolerance and predictable reactivity.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   49.69
  • LogP   1.3366
  • H_Acceptors   3
  • H_Donors   2
  • Rotatable_Bonds   5

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