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CS-W001157 4
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Methyl 2-chloro-5-formylbenzoate

  • CAS No. 199679-23-7

  • Cat. No. CS-0565433
  • Purity≥98%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

Methyl 2-chloro-5-formylbenzoate|CS-0565433

Structure of 199679-23-7

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General Information

  • CAS No. 199679-23-7
  • Cat. No. CS-0565433
  • Purity ≥98%
  • MDL No. None
  • Storage 4°C, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₇ClO₃
  • Molecular Weight 198.60
  • Synonym(s) None
  • SMILES O=C(OC)C1=CC(C=O)=CC=C1Cl

Description

Methyl 2-chloro-5-formylbenzoate features a formyl group at the para position relative to a chlorinated benzene ring, enabling direct functionalization in synthetic sequences. This electron-deficient aromatic aldehyde integrates readily into cross-coupling reactions and serves as a key intermediate for pharmaceutical and agrochemical scaffolds.

Application

Methyl 2-chloro-5-formylbenzoate serves as a versatile synthetic intermediate for constructing biologically relevant heterocycles and functionalized aromatic systems. The ortho-chloro and para-formyl groups enable sequential transformations, including nucleophilic substitution, formylation, and transition-metal-catalyzed coupling reactions. Its bench-stable nature and compatibility with standard purification protocols facilitate integration into multi-step syntheses of pharmaceuticals and agrochemicals.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   43.37
  • LogP   1.9391
  • H_Acceptors   3
  • H_Donors   0
  • Rotatable_Bonds   2

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